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Ixekizumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human IL17RA Therapeutic Antibody TAB-217 1mg Please Inquiry
Product Detail
Cat
TAB-217
Product Overview
Recombinant monoclonal antibody to IL17RA. Ixekizumab is a humanized monoclonal antibody used in the treatment of autoimmune diseases.
Target
IL17RA
Type
IgG4 - kappa
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in WB, IP, IF, FuncS, FC, Neut, ELISA and most other immunological methods.
CAS
1143503-69-8
Specificity
Tested positive against native human antigen.
Protein Construction
Immunoglobulin G4, anti-(human interleukin 17A) (human monoclonal LY2439821 γ4-chain), disulfide with human monoclonal LY2439821 kappa-chain, dimer
Predicted N terminal
H chain: QVQLVQS; L chain: DIVMTQT
Molecular Weight
146200
Purity
Purity >95% by SDS-PAGE.
Size
1mg
Storage
Store at -20°C. Avoid multiple freeze/thaw cycles.
Background
Antigen Description
Interleukin 17 Receptor Alpha is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis.
Function
interleukin-17 receptor activity; receptor activity;
Gene ID
23765
Synonyms
IL17RA; interleukin 17 receptor A; IL17R, interleukin 17 receptor; interleukin-17 receptor A; CD217; CDw217; hIL 17R; IL 17RA; IL-17 receptor A; IL17R; CANDF5; IL-17RA; hIL-17R; FLJ32274; FLJ36453; MGC10262;
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