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emibetuzumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human MET Therapeutic Antibody TAB-H24 1mg Please Inquiry
Product Detail
Cat
TAB-H24
Product Overview
Recombinant Humanized (from mouse) antibody to Human MET
Type
IgG4 - kappa
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FuncS, IF, Neut, ELISA, FC, IP, WB and most other immunological methods.
CAS
1365287-97-3
Specificity
MET (met proto-oncogene, hepatocyte growth factor (HGF) receptor, HGFR, scatter factor (SF) receptor, HGF/SF receptor, receptor tyrosine-protein kinase c-met, papillary renal cell carcinoma 2, RCCP2) [Homo sapiens]
Protein Construction
gamma4 heavy chain (1-441) [humanized VH (Homo sapiens IGHV1-2*02 (87.80%) – (IGHD) – IGHJ5*01 L123>T (110) (1-115)), IGHG4*01 (CH1(116-213), hinge S10>P (223) (214-225), CH2 F1.3>A (229), L1.2>A (230) (226-335), CH3 (336-440), CHS K2>del (441)) (116-441)],(129-215') –disulfide withkappa light chain (1'-215') [humanized V-KAPPA (Homo sapiens IGKV1-39*01 (84.40%) -IGKJ4*01) [7.3.9] (1'-108') – Homo sapiens IGKC*01(109'-215')]; dimer (221-221":224-224")-bisdisulfide
Purity
>95.0%. Determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Background
Antigen Description
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC s
Function
ATP binding; hepatocyte growth factor-activated receptor activity; nucleotide binding; protein binding; protein tyrosine kinase activity; protein tyrosine kinase activity; receptor activity;
Gene ID
4233
Synonyms
MET; met proto-oncogene (hepatocyte growth factor receptor); hepatocyte growth factor receptor; HGFR; RCCP2; SF receptor; HGF receptor; oncogene MET; HGF/SF receptor; proto-oncogene c-Met; scatter factor receptor; tyrosine-protein kinase Met; met proto-oncogene tyrosine kinase; AUTS9; c-Met;
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