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Onartuzumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human Met(c-Met) therapeutic Antibody Fab Fragment TAB-190-F(P) 1mg Please Inquiry
Product Detail
Cat
TAB-190-F(P)
Product Overview
Recombinant monoclonal antibody Fragment Fab to Met. Onartuzumab is a humanized monoclonal antibody designed for the treatment of cancer.
Target
Met(c-Met)
Type
Fab / Fc - G1 - kappa
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
E. coli
Applications
Suitable for use in FuncS, IF, Neut, ELISA, FC, IP, ICC and most other immunological methods.
CAS
1133766-06-9
Specificity
Tested positive against native human antigen.
Protein Construction
Immunoglobulin G1, anti-(human scatter factor receptor kinase)(human-mouse monoclonal MetMAb heavy chain), disulfide with human-mouse monoclonal MetMAb kappa-chain, disulfide with human-mouse monoclonal MetMAb heavy chain hinge region-CH2-CH3 domain-containing fragment
Predicted N terminal
H chain: EVQLVES; L chain: DIQMTQS
Molecular Weight
99146
Purity
>95.0% as determined by analysis by RP-HPLC.
Size
1mg
Storage
At -20°C for one year.
Background
Antigen Description
Receptor for hepatocyte growth factor and scatter factor. Has a tyrosine-protein kinase activity. Functions in cell proliferation, scattering, morphogenesis and survival.
Function
ATP binding; hepatocyte growth factor-activated receptor activity; nucleotide binding; protein binding; protein tyrosine kinase activity; protein tyrosine kinase activity; receptor activity;
Gene ID
4233
Synonyms
MET; met proto-oncogene (hepatocyte growth factor receptor); hepatocyte growth factor receptor; HGFR; RCCP2; SF receptor; HGF receptor; oncogene MET; HGF/SF receptor; proto-oncogene c-Met; scatter factor receptor; tyrosine-protein kinase Met; met proto-oncogene tyrosine kinase; AUTS9; c-Met;
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