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Narnatumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human RON Therapeutic Antibody TAB-184 1mg Please Inquiry
Product Detail
Cat
TAB-184
Product Overview
Recombinant monoclonal antibody to RON. Narnatumab is a human monoclonal antibody designed for the treatment of cancer.
Target
RON
Type
IgG1 - kappa
Immunogen
RE7 cells and MDCK cells overexpressing the human RON receptor in complete Freund`s adjuvant
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in IF, IP, Neut, FuncS, ELISA, FC, ICC and most other immunological methods.
CAS
1188275-92-4
Specificity
Tested positive against native human antigen.
Protein Construction
Immunoglobulin G1, anti-(human macrophage-stimulating protein receptor); human monoclonal IMC-RON8 γ1 heavy chain (225-214")-disulfide with human monoclonal IMC-RON8 kappa light chain, dimer (231-231"":234-234"")-bisdisulfide
Predicted N terminal
H chain: EVQLVES; L chain: EIVLTQS
Molecular Weight
145900
Purity
>95.0% as determined by analysis by SDS-PAGE.
Size
1mg
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Background
Antigen Description
Receptor for macrophage stimulating protein (MSP). Has a tyrosine-protein kinase activity.
Function
ATP binding; enzyme binding; macrophage colony-stimulating factor receptor activity; nucleotide binding; protein binding; receptor activity;
Gene ID
4486
Synonyms
MST1R; macrophage stimulating 1 receptor (c-met-related tyrosine kinase); PTK8, PTK8 protein tyrosine kinase 8 , RON; macrophage-stimulating protein receptor; CD136; CDw136; p185-Ron; MSP receptor; RON variant E2E3; MST1R variant RON30; MST1R variant RON62; soluble RON variant 1; soluble RON variant 2; soluble RON variant 3; soluble RON variant 4; c-met-related tyrosine kinase; PTK8 protein tyrosine kinase 8; RON; PTK8;
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