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Enavatuzumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human TWEAK receptor Therapeutic Antibody TAB-178 1mg Please Inquiry
Product Detail
Cat
TAB-178
Product Overview
Recombinant monoclonal antibody to TWEAK receptor. Drozitumab is a human monoclonal antibody designed for the treatment of cancers.
Target
TWEAK receptor
Type
IgG1 - kappa
Immunogen
Human Fn14 transfected P815.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in ELISA, FC, IP, FuncS, IF, Neut, ICC and most other immunological methods.
CAS
912628-39-8
Specificity
Tested positive against native human antigen.
Protein Construction
Immunoglobulin G1-lambda, anti-[Homo sapiens TNFRSF10B (tumor necrosis factor receptor superfamily member 10B, DR5, death receptor 5, TRAIL-R2, TNF-related apoptosis-inducing ligand receptor 2, TR-2, CD262)], Homo sapiens monoclonal antibody
Predicted N terminal
H chain: EVQLVES; L chain: DIQMTQS
Molecular Weight
143100
Purity
Purity >95% by SDS-PAGE.
Size
1mg
Storage
Store at -20°C. Avoid multiple freeze/thaw cycles.
Background
Antigen Description
Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.
Function
cytokine activity; cytokine activity; protein binding; receptor binding; tumor necrosis factor receptor binding;
Gene ID
8742
Synonyms
TNFSF12; tumor necrosis factor (ligand) superfamily, member 12; tumor necrosis factor ligand superfamily member 12; APO3L; DR3LG; TWEAK; APO3 ligand; APO3/DR3 ligand; TNF-related WEAK inducer of apoptosis; MGC20669; MGC129581;
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