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ligelizumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-IGHE Therapeutic Antibody TAB-755 1mg Please Inquiry
Product Detail
Cat
TAB-755
Product Overview
Recombinant humanized antibody expressed in CHO binding to human IGHE. Lampalizumab is a humanized monoclonal antibody designed for the treatment of geographic atrophy secondary to age-related macular degeneration.
Target
IGHE
Type
IgG1 - kappa
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in WB, IF, IP, Neut, FuncS, ELISA, FC and most other immunological methods.
CAS
1322627-61-1
Predicted N terminal
QVQLVQSG
Molecular Weight
46.96 kDa
Purity
Purity >95% by SDS-PAGE.
Size
1mg
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Background
Introduction
Ligelizumab is a humanized monoclonal antibody that binds to IGHE.
Antigen Description
The protein encoded by this gene is a member of the trypsin family of peptidases. The encoded protein is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. This protein is also a serine protease that is secreted by adipocytes into the bloodstream. Finally, the encoded protein has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology.
Gene ID
28223
Synonyms
IGHE; Immunoglobulin heavy constant epsilon;
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