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Anti-EPCAM Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human EPCAM Antibody Fab Fragment MOM-18112-F(P) 1mg Please Inquiry
Product Detail
Cat
MOM-18112-F(P)
Product Overview
Recombinant Humanized (from mouse) Antibody Fab Fragment is specific to Human EpCAM, expressed in E. coli
Target
EpCAM
Type
Fab Fragment based on Humanized (from mouse) Fab - G1 - kappa
Immunogen
LoVo cell line preparation (Human).
Species Reactivity
Human
Expression Host
E. coli
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Specificity
Tested positive against native antigen.
Protein Construction
Immunoglobulin G, anti-(tumor antigen 17-1A) (synthetic Fab fragment) fusion protein with bouganin (synthetic deimmunized)
Purity
>95%, by SDS-PAGE with silver staining, under reducing conditions.
Storage
Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.
Background
Antigen Description
May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.
Function
protein binding;
Gene ID
4072
Synonyms
EPCAM; epithelial cell adhesion molecule; antigen identified by monoclonal AUA1 , M4S1, MIC18, TACSTD1, tumor associated calcium signal transducer 1; 17 1A; 323/A3; CD326; CO 17A; EGP 2; EGP34; EGP40; Ep CAM; ESA; GA733 2; HEA125; KS1/4; KSA; Ly74; MH99; MK 1; MOC31; TACST 1; TROP1; epithelial glycoprotein 314; human epithelial glycoprotein-2; cell surface glycoprotein Trop-1; adenocarcinoma-associated antigen; tumor-associated calcium signal transducer 1; major gastrointestinal tumor-associated protein GA733-2; membrane component, chromosome 4, surface marker (35kD glycoprotein); M4S1; MK-1; DIAR5; EGP-2; MIC18; EGP314; HNPCC8; TACSTD1; GA733-2;
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