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Anti-GD3 ganglioside Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human GD3 ganglioside Antibody Fab Fragment MOM-18131-F(E) 1mg Please Inquiry
Product Detail
Cat
MOM-18131-F(E)
Product Overview
Recombinant Chimeric (mouse/human) Antibody Fab Fragment is bind to Human GD3 ganglioside, expressed in Chinese Hamster Ovary cells(CHO)
Target
GD3 ganglioside
Type
Fab Fragment based on Chimeric (mouse/human) IgG1 - kappa
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Specificity
Tested positive against native antigen.
Predicted N terminal
H chain: EVQLVES; L Chain: DIQMTQS
Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage
Store at -20°C. Avoid multiple freeze/thaw cycles.
Background
Introduction
This is a chimeric monoclonal antibody being developed for the treatment of malignant melanoma.
Antigen Description
Almost all melanomas, astrocytomas, a proportion of sarcomas, a small number of carcinomas, some nevi, as well as normal melanocytes express GD3 antigen. It is one of the most important markers for malignant melanoma. Antibodies to the GD3 ganglioside can induce partial remission of tumor growth in animals as well as in Humans via enhancement of cytotoxic and proliferative response of lymphocytes.
Keywords
GD3 ganglioside
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