Follow us on:
Dedication / Services
To provide 50000 services and products to global scientific research units every year

Anti-ITGA2B Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human ITGA2B Antibody Fab Fragment MOM-18015-F(E) 1mg Please Inquiry
Product Detail
Cat
MOM-18015-F(E)
Product Overview
Recombinant Chimeric (mouse/human) Antibody Fab Fragment is specific to Human CD41, expressed in Chinese Hamster Ovary cells(CHO)
Target
CD41
Type
Fab Fragment based on Chimeric (mouse/human) Fab - G1 - kappa
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Specificity
Tested positive against native antigen.
Protein Construction
Immunoglobulin G1, anti-(human integrin alpha Iib beta 3) Fab fragment (human-mousemonoclonal c7E3 clone gamma 1-chain), disulfide with human-mouse monoclonal c7E3 clone kappa-chain
Purity
>95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Background
Antigen Description
Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.
Function
extracellular matrix binding; identical protein binding; protein binding; receptor activity;
Gene ID
3674
Synonyms
ITGA2B; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); GP2B, integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B); integrin alpha-IIb; CD41; CD41B; GPalpha IIb; platelet-specific antigen BAK; platelet membrane glycoprotein IIb; platelet fibrinogen receptor, alpha subunit; GT; GTA; GP2B; HPA3; GPIIb; BDPLT2;
Download Datasheet:

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us

Online Inquiry
Please input "biolabs"(case insensitive) as verification code.
Loading...
Contact Us

USA
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email: 

Europe
Tel: 44-207-097-1828


© 2007 - 2017 Creative-Biolabs All Rights Reserved