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Anti-ITGA4 Antibody scFv

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human ITGA4 Antibody scFv Fragment MOM-18135-S(P) 1mg Please Inquiry
Product Detail
Cat
MOM-18135-S(P)
Product Overview
Recombinant Humanized (from rat) Antibody scFv Fragment specifically binds to Human Integrin alpha 4 beta 7, expressed in E. coli
Target
Integrin alpha 4 beta 7
Type
scFv Fragment from Humanized (from rat) IgG1 - kappa
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
E. coli
Applications
Suitable for use in ELISA, WB, Neut and most other immunological methods.
Specificity
Tested positive against native antigen.
Purity
>95.0% as determined by analysis by RP-HPLC.
Storage
Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Background
Antigen Description
Integrin alpha 4 beta 7, also known as, the lymphocyte Peyer"s patch adhesion molecule (LPAM1) is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. The alpha 4 beta 7 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer"s patches and intestinal lamina propria.
Function
fibronectin binding; protein binding; receptor activity;
Gene ID
3676
Synonyms
ITGA4; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor); CD49D; integrin alpha-4; CD49d; 269C wild type; integrin alpha 4; integrin alpha-IV; VLA-4 subunit alpha; integrin alpha-4 subunit; CD49 antigen-like family member D; antigen CD49D, alpha-4 subunit of VLA-4 receptor; very late activation protein 4 receptor, alpha 4 subunit; IA4; MGC90518;
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