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Anti-ITGA5 Antibody

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human ITGA5 Antibody MOM-18077 1mg Please Inquiry
Product Detail
Cat
MOM-18077
Product Overview
Recombinant Chimeric (mouse/human) Antibody is directed against Human Integrin alpha 5 beta 1, expressed in Chinese Hamster Ovary cells(CHO)
Target
Integrin alpha 5 beta 1
Type
Chimeric (mouse/human) IgG4
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in IF, IP, Neut, FuncS, ELISA, FC, IHC and most other immunological methods.
Specificity
Tested positive against native antigen.
Protein Construction
Immunoglobulin G4, anti-(human a5b1 integrin) (human-mouse clone p200-M heavy chain), disulfide with human-mouse clone p200-M k-chain, dimer
Predicted N terminal
H Chain: MAVLGLL; L Chain: MDFQVQV
Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage
Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
Background
Antigen Description
This protein belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha V chain. Alpha chain V undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
Function
integrin binding; platelet-derived growth factor receptor binding; protein binding; receptor activity; vascular endothelial growth factor receptor 2 binding;
Gene ID
3678
Synonyms
ITGA5; integrin, alpha 5 (fibronectin receptor, alpha polypeptide); FNRA; integrin alpha-5; CD49e; VLA-5; integrin alpha-F; CD49 antigen-like family member E; fibronectin receptor subunit alpha; fibronectin receptor, alpha subunit; very late activation protein 5, alpha subunit; VLA5A;
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