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Anti-ITGAV Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human ITGAV Antibody Fab Fragment MOM-18076-F(E) 1mg Please Inquiry
Product Detail
Cat
MOM-18076-F(E)
Product Overview
Recombinant Human Antibody Fab Fragment binds selectively to Human CD51, expressed in Chinese Hamster Ovary cells(CHO)
Target
CD51
Type
Fab Fragment based on Human IgG1 - kappa
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Specificity
Tested positive against native antigen.
Predicted N terminal
H Chain: QVQLVES; L Chain: EIVLTQS
Purity
>95.0% as determined by analysis by RP-HPLC.
Storage
Store at -20°C. Avoid multiple freeze/thaw cycles.
Background
Antigen Description
The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi"s sarcoma lesions.
Function
contributes_to insulin-like growth factor I binding; contributes_to opsonin binding; protein binding; protein kinase C alpha binding; contributes_to protein kinase C binding; receptor activity; transforming growth factor beta binding;
Gene ID
3685
Synonyms
ITGAV; integrin, alpha V; antigen identified by monoclonal L230 , integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) , MSK8, vitronectin receptor , VNRA, VTNR; integrin alpha-V; CD51; integrin alphaVbeta3; vitronectin receptor subunit alpha; antigen identified by monoclonal L230; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51); MSK8; VNRA; VTNR; DKFZp686A08142;
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