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Anti-ITGAV+ITGB3 Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human ITGAV+ITGB3 Antibody Fab Fragment MOM-18025-F(E) 1mg Please Inquiry
Product Detail
Cat
MOM-18025-F(E)
Product Overview
Recombinant Humanized (from mouse) Antibody Fab Fragment is against Human CD51+CD61, expressed in Chinese Hamster Ovary cells(CHO cells)
Target
CD51+CD61
Type
Fab Fragment based on Humanized (from mouse) IgG1
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Specificity
Tested positive against native antigen.
Purity
Purity >95% by SDS-PAGE.
Storage
Store at -20°C. Avoid multiple freeze/thaw cycles.
Background
Antigen Description
Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. They are known to participate in cell adhesion as well as cell-surface mediated signalling. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. CD51 encodes integrin alpha chain V. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Alpha-V integrins have been implicated in many developmental processes and are therapeutic targets for inhibition of angiogenesis and osteoporosis.
Keywords
ITGAV; integrin, alpha V; antigen identified by monoclonal L230, integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51), MSK8, vitronectin receptor , VNRA, VTNR; integrin alpha-V; CD51; integrin alphaVbeta3; vitronectin receptor subunit
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