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Anti-SDC1 Antibody

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human SDC1 Antibody MOM-18197 1mg Please Inquiry
Product Detail
Cat
MOM-18197
Product Overview
Recombinant Chimeric (mouse/human) Antibody is specific to Human SDC1, expressed in Chinese Hamster Ovary cells(CHO)
Target
SDC1
Type
Chimeric (mouse/human) IgG4 - kappa
Immunogen
U266 cell line
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in IP, IF, FuncS, FC, Neut, ELISA and most other immunological methods.
Specificity
Tested positive against native antigen.
Protein Construction
Immunoglobulin G4-kappa, anti-[Homo sapiens SDC1 (syndecan-1, CD138)], chimeric monoclonal antibody conjugated to maytansinoid DM4
Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage
Store at -20°C. Avoid multiple freeze/thaw cycles.
Background
Antigen Description
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.
Function
cytoskeletal protein binding; glycoprotein binding; lipoprotein lipase activity; protein C-terminus binding; protein binding;
Gene ID
6382
Synonyms
SDC1; syndecan 1; SDC; syndecan-1; CD138; SYND1; syndecan; syndecan proteoglycan 1; CD138 antigen; heparan sulfate proteoglycan fibroblast growth factor receptor;
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