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Anti-TAG-72 Antibody

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human TAG-72 Antibody MOM-18002 1mg Please Inquiry
Product Detail
Cat
MOM-18002
Product Overview
Recombinant Mouse Antibody is bind to Human TAG72, expressed in Chinese Hamster Ovary cells(CHO)
Target
TAG72
Type
Mouse IgG1
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in WB, ELISA, IP, FC, FuncS, Neut, IF and most other immunological methods.
Specificity
Tested positive against native antigen.
Protein Construction
Immunoglobulin G1 (mouse monoclonal B72.3 anti-human glycoprotein TAG-72), disulfide with mouse monoclonal B72.3 light chain, dimer
Predicted N terminal
H Chain: QVQLQQS; L Chain: DIQMTQS
Purity
>95%, by SDS-PAGE with silver staining, under reducing conditions.
Storage
Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
Background
Introduction
This monoclonal antibody can be attached to the chelator pentetic acid (DTPA) linked to the tripeptide glycine (G) – L-tyrosine (Y) – L-lysine (K), which chelates Indium 111 and binds selectively to cell-surface TAG-72 expressed on colorectal tumors. This product has the same active ingredient as Satumomab Pendetide.
Antigen Description
The majority of human adenocarcinomas including colorectal, pancreatic, gastric, ovarian, endometrial, mammary, and non-small cell lung cancer display some cell populations that are positive for TAG72. About 60% of carcinoma patients express TAG72 in their sera. TAG72 is reportedly useful in distinguishing pulmonary adenocarcinomas from pleural mesotheliomas.
Keywords
CA 72.4; TAG 72; Tumor associated Glycoprotein 72; OncoScint CR103; Satumomab Pendetide
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