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Anti-TNF Antibody

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human TNF Antibody MOM-18010 1mg Please Inquiry
Product Detail
Cat
MOM-18010
Product Overview
Recombinant Human Antibody is directed against Human TNF, expressed in Chinese Hamster Ovary cells(CHO)
Target
TNF
Type
Human IgG1 - kappa
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FuncS, IF, Neut, ELISA and most other immunological methods.
Specificity
Tested positive against native antigen.
Protein Construction
Immunoglobulin G1, anti-(human tumor necrosis factor) (human monoclonal D2E7 heavy chain), disulfide with human monoclonal D2E7 light chain, dimer
Predicted N terminal
H chain: EVQLVES; L Chain: DIQMTQS
Purity
>95.0% as determined by analysis by SDS-PAGE.
Storage
4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.
Background
Antigen Description
Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.
Function
cytokine activity; identical protein binding; protease binding; protein binding; transcription regulatory region DNA binding; tumor necrosis factor receptor binding;
Gene ID
7124
Synonyms
TNF; tumor necrosis factor; TNFA, tumor necrosis factor (TNF superfamily, member 2); DIF; TNF superfamily; member 2; TNF alpha; TNFSF2; TNF-a; cachectin; APC1 protein; TNF, monocyte-derived; TNF, macrophage-derived; TNF superfamily, member 2; tumor necrosis factor alpha; tumor necrosis factor-alpha; tumor necrosis factor ligand superfamily member 2; TNFA; TNF-alpha;
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