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Anti-TNF Antibody

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human TNF Antibody MOM-18254 1mg Please Inquiry
Product Detail
Cat
MOM-18254
Product Overview
Recombinant Human Antibody binds selectively to Human TNF, expressed in Chinese Hamster Ovary cells(CHO)
Target
TNF
Type
Human [V-kappa]2 - Fc
Immunogen
Full length native protein (purified) (Human).
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in WB, ELISA, FC, IP, FuncS, IF, Neut and most other immunological methods.
Specificity
Tested positive against native antigen.
Protein Construction
Immunoglobulin (V-kappa)2-Fc gamma1, anti-[Homo sapiens TNF (tumor necrosis factor, TNF superfamily member 2, TNFSF2, TNFalpha, TNFA)], Homo sapiens monoclonal antibody
Predicted N terminal
H chain: DIQMTQS
Purity
Purity >95% by SDS-PAGE.
Storage
Store at -20°C. Avoid multiple freeze/thaw cycles.
Background
Antigen Description
Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.
Function
cytokine activity; identical protein binding; protease binding; protein binding; transcription regulatory region DNA binding; tumor necrosis factor receptor binding;
Gene ID
7124
Synonyms
TNF; tumor necrosis factor; TNFA, tumor necrosis factor (TNF superfamily, member 2); DIF; TNF superfamily; member 2; TNF alpha; TNFSF2; TNF-a; cachectin; APC1 protein; TNF, monocyte-derived; TNF, macrophage-derived; TNF superfamily, member 2; tumor necrosis factor alpha; tumor necrosis factor-alpha; tumor necrosis factor ligand superfamily member 2; TNFA; TNF-alpha;
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