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Anti-TNFRSF10B Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human TNFRSF10B Antibody Fab Fragment MOM-18203-F(E) 1mg Please Inquiry
Product Detail
Cat
MOM-18203-F(E)
Product Overview
Recombinant Human Antibody Fab Fragment is directed against Human DR5, expressed in Chinese Hamster Ovary cells(CHO)
Target
DR5
Type
Fab Fragment based on Human IgG1 - kappa
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Specificity
Tested positive against native antigen.
Predicted N terminal
H chain: QLPGKGL; L Chain: EIVLTQS
Purity
>95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.
Storage
At -20°C for one year.
Background
Antigen Description
Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.
Function
TRAIL binding; protein binding; receptor activity;
Gene ID
8795
Synonyms
TNFRSF10B; tumor necrosis factor receptor superfamily, member 10b; tumor necrosis factor receptor superfamily member 10B; CD262; DR5; KILLER; TRAIL R2; TRICK2A; TRICKB; Fas-like protein; death receptor 5; cytotoxic TRAIL receptor-2; apoptosis inducing receptor TRAIL-R2; apoptosis inducing protein TRICK2A/2B; TNF-related apoptosis-inducing ligand receptor 2; death domain containing receptor for TRAIL/Apo-2L; tumor necrosis factor receptor-like protein ZTNFR9; p53-regulated DNA damage-inducible cell death receptor(killer); TRICK2; ZTNFR9; TRAILR2; TRICK2B; TRAIL-R2; KILLER/DR5;
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