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Anti-mapt Antibody

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human mapt Antibody MOM-18495 1mg Please Inquiry
Product Detail
Cat
MOM-18495
Product Overview
Recombinant Mouse Antibody binds selectively to Human MAPT, expressed in Chinese Hamster Ovary cells(CHO)
Target
MAPT
Type
IgG
Immunogen
Purified bovine microtubule associated proteins.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in Neut, FuncS, ELISA, FC and most other immunological methods.
Specificity
Tested positive against native antigen.
Purity
Purity >95% by SDS-PAGE.
Storage
Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.
Background
Antigen Description
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Function
SH3 domain binding; apolipoprotein E binding; enzyme binding; lipoprotein particle binding; microtubule binding; protein binding; structural constituent of cytoskeleton;
Gene ID
4137
Synonyms
MAPT; microtubule-associated protein tau; DDPAC, MAPTL; FLJ31424; FTDP 17; G protein beta1/gamma2 subunit interacting factor 1; MGC138549; microtubule associated protein tau; isoform 4; MSTD; MTBT1; MTBT2; PPND; tau; TAU; PHF-tau; paired helical filament-tau; neurofibrillary tangle protein; microtubule-associated protein tau, isoform 4; G protein beta1/gamma2 subunit-interacting factor 1; DDPAC; MAPTL; FTDP-17
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