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Anti-tnfrsf1a Antibody

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human tnfrsf1a Antibody MOM-18510 1mg Please Inquiry
Product Detail
Cat
MOM-18510
Product Overview
Recombinant Mouse Antibody is specific to Human TNFRSF1A, expressed in Chinese Hamster Ovary cells(CHO)
Target
TNFRSF1A
Type
IgG
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in Neut, FuncS, ELISA, FC, IHC and most other immunological methods.
Specificity
Tested positive against native antigen.
Purity
>95.0%. Determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Storage
At -20°C for one year.
Background
Antigen Description
Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
Function
protease binding; protein binding; receptor activity; tumor necrosis factor binding; tumor necrosis factor-activated receptor activity;
Gene ID
7132
Synonyms
TNFRSF1A; tumor necrosis factor receptor superfamily, member 1A; TNFR1; tumor necrosis factor receptor superfamily member 1A; CD120a; TNF R; TNF R I; TNF R55; TNFAR; TNFR60; TNF-R1; TNF-RI; TNFR-I; tumor necrosis factor-alpha receptor; tumor necrosis factor receptor type 1; tumor necrosis factor binding protein 1; tumor necrosis factor receptor 1A isoform beta; FPF; p55; p60; TBP1; TNF-R; p55-R; TNFR55; TNF-R-I; TNF-R55; MGC19588
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