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Magic™ Membrane Protein Human ADGRL1 (Adhesion G protein-coupled receptor L1) Full Length (CAT#: MPC0018K) Made to Order

This product is a 162.7 kDa Human ADGRL1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ADGRL1
  • Protein Length
  • Full length
  • Protein Class
  • GPCR
  • Molecular Weight
  • 162.7 kDa
  • TMD
  • 7
  • Sequence
  • MARLAAVLWNLCVTAVLVTSATQGLSRAGLPFGLMRRELACEGYPIELRC
    PGSDVIMVENANYGRTDDKICDADPFQMENVQCYLPDAFKIMSQRCNNRT
    QCVVVAGSDAFPDPCPGTYKYLEVQYDCVPYKVEQKVFVCPGTLQKVLEP
    TSTHESEHQSGAWCKDPLQAGDRIYVMPWIPYRTDTLTEYASWEDYVAAR
    HTTTYRLPNRVDGTGFVVYDGAVFYNKERTRNIVKYDLRTRIKSGETVIN
    TANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEGNNGRLVVSQLNPYTL
    RFEGTWETGYDKRSASNAFMVCGVLYVLRSVYVDDDSEAAGNRVDYAFNT
    NANREEPVSLTFPNPYQFISSVDYNPRDNQLYVWNNYFVVRYSLEFGPPD
    PSAGPATSPPLSTTTTARPTPLTSTASPAATTPLRRAPLTTHPVGAINQL
    GPDLPPATAPVPSTRRPPAPNLHVSPELFCEPREVRRVQWPATQQGMLVE
    RPCPKGTRGIASFQCLPALGLWNPRGPDLSNCTSPWVNQVAQKIKSGENA
    ANIASELARHTRGSIYAGDVSSSVKLMEQLLDILDAQLQALRPIERESAG
    KNYNKMHKRERTCKDYIKAVVETVDNLLRPEALESWKDMNATEQVHTATM
    LLDVLEEGAFLLADNVREPARFLAAKENVVLEVTVLNTEGQVQELVFPQE
    EYPRKNSIQLSAKTIKQNSRNGVVKVVFILYNNLGLFLSTENATVKLAGE
    AGPGGPGGASLVVNSQVIAASINKESSRVFLMDPVIFTVAHLEDKNHFNA
    NCSFWNYSERSMLGYWSTQGCRLVESNKTHTTCACSHLTNFAVLMAHREI
    YQGRINELLLSVITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLC
    INLFLAELLFLVGIDKTQYEIACPIFAGLLHYFFLAAFSWLCLEGVHLYL
    LLVEVFESEYSRTKYYYLGGYCFPALVVGIAAAIDYRSYGTEKACWLRVD
    NYFIWSFIGPVSFVIVVNLVFLMVTLHKMIRSSSVLKPDSSRLDNIKSWA
    LGAIALLFLLGLTWAFGLLFINKESVVMAYLFTTFNAFQGVFIFVFHCAL
    QKKVHKEYSKCLRHSYCCIRSPPGGTHGSLKTSAMRSNTRYYTGTQSRIR
    RMWNDTVRKQTESSFMAGDINSTPTLNRGTMGNHLLTNPVLQPRGGTSPY
    NTLIAESVGFNPSSPPVFNSPGSYREPKHPLGGREACGMDTLPLNGNFNN
    SYSLRSGDFPPGDGGPEPPRGRNLADAAAFEKMIISELVHNNLRGSSSAA
    KGPPPPEPPVPPVPGGGGEEEAGGPGGADRAEIELLYKALEEPLLLPRAQ
    SVLYQSDLDESESCTAEDGATSRPLSSPPGRDSLYASGANLRDSPSYPDS
    SPEGPSEALPPPPPAPPGPPEIYYTSRPPALVARNPLQGYYQVRRPSHEG
    YLAAPGLEGPGPDGDGQMQLVTSL

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • ADGRL1
  • Full Name
  • Adhesion G protein-coupled receptor L1
  • Introduction
  • This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms.
  • Alternative Names
  • CL1; LEC2; CIRL1; LPHN1; CIRL-1; calcium-independent alpha-latrotoxin receptor 1; latrophilin-1; lectomedin-2; ADGRL1; Adhesion G protein-coupled receptor L1

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