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Magic™ Membrane Protein Human CLN8 (CLN8 transmembrane ER and ERGIC protein) Full Length (CAT#: MPC1583K) Made to Order

This product is a 32.7 kDa Human CLN8 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CLN8
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 32.7 kDa
  • TMD
  • 5
  • Sequence
  • MNPASDGGTSESIFDLDYASWGIRSTLMVAGFVFYLGVFVVCHQLSSSLN
    ATYRSLVAREKVFWDLAATRAVFGVQSTAAGLWALLGDPVLHADKARGQQ
    NWCWFHITTATGFFCFENVAVHLSNLIFRTFDLFLVIHHLFAFLGFLGCL
    VNLQAGHYLAMTTLLLEMSTPFTCVSWMLLKAGWSESLFWKLNQWLMIHM
    FHCRMVLTYHMWWVCFWHWDGLVSSLYLPHLTLFLVGLALLTLIINPYWT
    HKKTQQLLNPVDWNFAQPEAKSRPEGNGQLLRKKRP

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • CLN8
  • Full Name
  • CLN8 transmembrane ER and ERGIC protein
  • Introduction
  • This gene encodes a transmembrane protein belonging to a family of proteins containing TLC domains, which are postulated to function in lipid synthesis, transport, or sensing. The protein localizes to the endoplasmic reticulum (ER), and may recycle between the ER and ER-Golgi intermediate compartment. Mutations in this gene are associated with a disorder characterized by progressive epilepsy with cognitive disabilities (EPMR), which is a subtype of neuronal ceroid lipofuscinoses (NCL). Patients with mutations in this gene have altered levels of sphingolipid and phospholipids in the brain.
  • Alternative Names
  • CLN8; EPMR; TLCD6; C8orf61; protein CLN8; ceroid-lipofuscinosis, neuronal 8; CLN8 transmembrane ER and ERGIC protein

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