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Magic™ Membrane Protein Human GALNT1 (Polypeptide N-acetylgalactosaminyltransferase 1) Expressed in NS0 for Antibody Discovery, Partial (41-559aa) (CAT#: MPX0516K)

Datasheet
This product is a 60 kDa Human GALNT1 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GALNT1
  • Protein Length
  • Partial (41-559aa)
  • Protein Class
  • Transferase
  • Molecular Weight
  • 60 kDa
  • TMD
  • 1
  • Sequence
  • GLPAGDVLEP
    VQKPHEGPGEMGKPVVIPKEDQEKMKEMFKINQFNLMASEMIALNRSLPD
    VRLEGCKTKVYPDNLPTTSVVIVFHNEAWSTLLRTVHSVINRSPRHMIEE
    IVLVDDASERDFLKRPLESYVKKLKVPVHVIRMEQRSGLIRARLKGAAVS
    KGQVITFLDAHCECTVGWLEPLLARIKHDRRTVVCPIIDVISDDTFEYMA
    GSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDR
    DYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKAT
    PYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDISSRV
    GLRHKLQCKPFSWYLENIYPDSQIPRHYFSLGEIRNVETNQCLDNMARKE
    NEKVGIFNCHGMGGNQVFSYTANKEIRTDDLCLDVSKLNGPVTMLKCHHL
    KGNQLWEYDPVKLTLQHVNSNQCLDKATEEDSQVPSIRDCNGSRSQQWLL
    RNVTLPEIF

Product Description

  • Activity
  • Yes
  • Expression Systems
  • NS0
  • Tag
  • 6xHis tag at the N-terminus
  • Protein Format
  • Soluble
  • Endotoxin
  • <1.0 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain at 5 μg per lane.
  • Buffer
  • Supplied as a 0.2 μm filtered solution in Tris and NaCl.

Target

  • Target Protein
  • GALNT1
  • Full Name
  • Polypeptide N-acetylgalactosaminyltransferase 1
  • Introduction
  • This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. Transcript variants derived from this gene that utilize alternative polyA signals have been described in the literature.
  • Alternative Names
  • GALNT1; GALNAC-T1; GalNAc transferase 1; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1); polypeptide GalNAc transferase 1; pp-GaNTase 1; protein-UDP acetylgalactosaminyltransferase 1; Polypeptide N-acetylgalactosaminyltransferase 1

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