Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsWith over a decade of experience in phage display technology, Creative Biolabs can provide a series of antibody or peptide libraries that are available for licensing or direct screening. These ready-to-use libraries are invaluable resources for isolating target-specific binders for various research, diagnostic or therapeutic applications. Highlights
Creative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
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Virus-like particles (VLPs) resemble their corresponding native viruses with similar overall structures but lose original infectious ability due to the absence of viral genome. VLPs are symmetrically built from hundreds of coat proteins, which can be genetically engineered to present a regular arrangement of epitope chains on the desired positions of the outer surface. Currently, VLPs have been widely applied for a variety of applications such as vaccines, antibody development, delivery systems, bioimaging, and cell targeting. Of note, VLPs have proven excellent utility in membrane protein display.
Membrane Protein VLPs (MP-VLPs) are non-infectious virus-like particles (VLPs, about 150 nm in diameter) that display highly-expressed copies of specific membrane proteins in their native conformation. MP-VLPs are produced from mammalian cells by co-expressing the retroviral structural core polyprotein (gag) and the target membrane protein. Retroviral gag core proteins self-assemble at the plasma membrane, where they bud from the host cells over-expressing a membrane protein of interest, enabling the formation of MP-VLPs.
MP-VLPs display highly-expressed copies of membrane proteins in their native conformation, providing an alternative to membrane protein stable cell lines, crude membrane, detergent-solubilized proteins and other membrane protein preparation strategies (liposome, nanodisc). MP-VLPs can be used for a wide range of applications.
Creative Biolabs has been dedicated to providing first-class membrane protein production service using a variety of strategies. Based on our leading-edge platform, we have successfully produced, purified, stabilized, and characterized many challenging membrane protein targets. With advanced Magic™ MP-VLPs production platform, Creative Biolabs offers custom end-to-end MP-VLPs production services for the membrane protein of interest, including plasmid construction, pilot expression, quality control, scale-up expression, and product delivery. Comprehensive QC methods are available for the MP-VLPs quality control, ensuring the high-quality MP-VLPs. For soluble proteins, we are able to capture the protein on the surface of VLPs via biotin-streptavidin interaction. Please feel free to inquire us for more information.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
