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NativeExtract™ Human GPR119 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX252)

This product is recombinant Human GPR119 protein in native nanodisc form. The synthetic compound we developed can solubilize the GPR119 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GPR119
  • Protein Length
  • Full length
  • Molecular Weight
  • 36.9kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • GPR119
  • Full Name
  • G protein-coupled receptor 119
  • Introduction
  • This gene encodes a member of the rhodopsin subfamily of G-protein-coupled receptors that is expressed in the pancreas and gastrointestinal tract. The encoded protein is activated by lipid amides including lysophosphatidylcholine and oleoylethanolamide and may be involved in glucose homeostasis. This protein is a potential drug target in the treatment of type 2 diabetes.
  • Alternative Names
  • GPCR2; glucose-dependent insulinotropic receptor; G-protein coupled receptor 2; GPR119; G protein-coupled receptor 119

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