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NativeExtract™ Human GPR132 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX379)

This product is recombinant Human GPR132 protein in native nanodisc form. The synthetic compound we developed can solubilize the GPR132 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GPR132
  • Protein Length
  • Full length
  • Molecular Weight
  • 42.5 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • GPR132
  • Full Name
  • G protein-coupled receptor 132
  • Introduction
  • This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein was reported to be a receptor for lysophosphatidylcholine action, but PubMedID: 15653487 retracts this finding and instead suggests this protein to be an effector of lysophosphatidylcholine action. This protein may have proton-sensing activity and may be a receptor for oxidized free fatty acids. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • G2A; probable G-protein coupled receptor 132; G2 accumulation protein; GPR132; G protein-coupled receptor 132

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