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NativeExtract™ Human GPR150 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX243)

This product is recombinant Human GPR150 protein in native nanodisc form. The synthetic compound we developed can solubilize the GPR150 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GPR150
  • Protein Length
  • Full length
  • Molecular Weight
  • 46.4kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • GPR150
  • Full Name
  • G protein-coupled receptor 150
  • Introduction
  • This gene encodes an orphan member of the class A rhodopsin-like family of G-protein-coupled receptors (GPCRs). Within the rhodopsin-like family, this gene is a member of the vasopressin-like subfamily that also includes vasopressin and oxytocin receptors. The silencing of this gene, due to promoter methylation, is associated with ovarian cancer progression. All GPCRs have a transmembrane domain that includes seven transmembrane alpha-helices. A general feature of GPCR signaling is the agonist-induced conformational change in the receptor, leading to activation of the heterotrimeric G protein. The activated G protein then binds to and activates numerous downstream effector proteins, which generate second messengers that mediate a broad range of cellular and physiological processes.
  • Alternative Names
  • PGR11; probable G-protein coupled receptor 150; seven transmembrane helix receptor; GPR150; G protein-coupled receptor 150

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