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NativeExtract™ Human GPR3 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX211)

Datasheet
This product is recombinant Human GPR3 protein in native nanodisc form. The synthetic compound we developed can solubilize the GPR3 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GPR3
  • Protein Length
  • Full length
  • Molecular Weight
  • 35kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • GPR3
  • Full Name
  • G protein-coupled receptor 3
  • Introduction
  • This gene is a member of the G protein-coupled receptor family and is found in the cell membrane. G protein-coupled receptors, characterized by a seven transmembrane domain motif, are involved in translating outside signals into G protein mediated intracellular effects. The encoded protein activates adenylate cyclase and modulates amyloid-beta production in a mouse model, suggesting that it may play a role in Alzheimer's disease.
  • Alternative Names
  • ACCA; G-protein coupled receptor 3; ACCA orphan receptor; adenylate cyclase constitutive activator; GPR3; G protein-coupled receptor 3

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