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NativeExtract™ Human HTR5A Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX343)

Datasheet
This product is recombinant Human HTR5A protein in native nanodisc form. The synthetic compound we developed can solubilize the HTR5A protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • HTR5A
  • Protein Length
  • Full length
  • Molecular Weight
  • 40.3kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • HTR5A
  • Full Name
  • 5-hydroxytryptamine receptor 5A
  • Introduction
  • The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. The gene described in this record is a member of 5-hydroxytryptamine (serotonin) receptor family and encodes a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization.
  • Alternative Names
  • 5-HT5A; 5-HT-5; 5-HT-5A; 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled; HTR5A; 5-hydroxytryptamine receptor 5A

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