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NativeExtract™ Human KISS1R Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX180)

Datasheet
This product is recombinant Human KISS1R protein in native nanodisc form. The synthetic compound we developed can solubilize the KISS1R protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KISS1R
  • Protein Length
  • Full length
  • Molecular Weight
  • 42.6kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • KISS1R
  • Full Name
  • KISS1 receptor
  • Introduction
  • The protein encoded by this gene is a galanin-like G protein-coupled receptor that binds metastin, a peptide encoded by the metastasis suppressor gene KISS1. The tissue distribution of the expressed gene suggests that it is involved in the regulation of endocrine function, and this is supported by the finding that this gene appears to play a role in the onset of puberty. Mutations in this gene have been associated with hypogonadotropic hypogonadism and central precocious puberty.
  • Alternative Names
  • HH8; CPPB1; GPR54; AXOR12; KISS-1R; HOT7T175; kiSS-1 receptor; G protein-coupled receptor 54; G-protein coupled receptor OT7T175; hypogonadotropin-1; kisspeptins receptor; metastin receptor; KISS1R; KISS1 receptor

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