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NativeExtract™ Human XCR1 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX375)

Datasheet
This product is recombinant Human XCR1 protein in native nanodisc form. The synthetic compound we developed can solubilize the XCR1 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • XCR1
  • Protein Length
  • Full length
  • Molecular Weight
  • 38.5 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • XCR1
  • Full Name
  • X-C motif chemokine receptor 1
  • Introduction
  • The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Several alternatively spliced transcript variants encoding the same protein have been found for this gene.
  • Alternative Names
  • GPR5; CCXCR1; chemokine XC receptor 1; G protein-coupled receptor 5; XC chemokine receptor 1; chemokine (C motif) XC receptor 1; chemokine (C motif) receptor 1; lymphotactin receptor; XCR1; X-C motif chemokine receptor 1

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