Can the CD26 Polyclonal Antibody be used in research on immune regulation?

Yes, due to CD26's involvement in T-cell activation and immune response modulation, this antibody is crucial for exploring immune regulatory mechanisms.

Category: Non-Human Primate (NHP) related Antibody Products

CD26 Polyclonal Antibody (NHP-AB260)

Product Overview Detailed Product Description Technical Specifications Product Property Target Information Downloadable Resources FAQs Customer Reviews

This product is an antibody that was generated by immunizing rabbit against N-Terminal domain of human. It is used only in in vitro assays.

Introduction: CD26 (dipeptidyl peptidase IV, DPP IV), adenosine deaminase (ADA) binding protein) is a homodimeric atypical serine protease belonging to the prolyl oligopeptidase family. CD26 is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti CD3-induced IL - 2 production. CD26 identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. Further, CD26 is an intrinsic membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. Alterations in CD26 peptidase activity are characteristic of malignant transformation, and the enzymatic activity increases dramatically with tumor grade and severity. CD26 is expressed in various blood cell types, but also in cells that are histogenetically related to activated fibroblasts. Alterations in CD26 density have been reported on circulating monocytes and CD4+ T cells during rheumatoid arthritis and systemic lupus erythematosus.

Conjugate: None

Applications: IHC

Host Species: Rabbit

Species Reactivity: Chimpanzee; Gibbon; Gorilla; Human

Immunogen: N-Terminal domain of human

Purification: Immunoaffinity Chromatography

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 0.1% sodium azide.

Storage: Short term: 4˚C. Long term: Store at -20˚C. Avoid freeze-thaw cycles.

Clonality: Polyclonal

Alternative Names: ADABP; ADCP-2; Adenosine deaminase complexing protein 2; Bile canaliculus domain-specific membrane glycoprotein; CD26; Dipeptidyl peptidase 4; Dipeptidyl peptidase 4 60 kDa soluble form; Dipeptidyl peptidase 4 membrane form; Dipeptidyl peptidase 4 soluble form; Dipeptidyl peptidase IV; Dipeptidyl peptidase IV 60 kDa soluble form; Dipeptidyl peptidase IV membrane form; Dipeptidyl peptidase IV soluble form; dipeptidyl-peptidase 4; dipeptidyl peptidase 4; dipeptidyl peptidase IV (CD26, adenosine deaminase complexing protein 2); DPP IV; DPP-IV; GP110 glycoprotein; T-cell activation antigen CD26; TP103

Entrez Gene ID: 1803

CD26 Polyclonal Antibody (NHP-AB260) Data Sheet: Detailed information. datasheet

Q 1: Can the CD26 Polyclonal Antibody be used in research on immune regulation?
A: Yes, due to CD26's involvement in T-cell activation and immune response modulation, this antibody is crucial for exploring immune regulatory mechanisms.

High Specificity & High Quality
The CD26 Polyclonal Antibody has been instrumental in advancing our cancer research. Its specificity and high quality have allowed us to accurately study CD26's role in tumor biology.
Excellent Reliability
Utilizing the CD26 Polyclonal Antibody in our immunology studies has provided us with critical insights into immune regulation. The product's reliability has significantly contributed to our research outcomes.

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Fig.1 Obesity can be counteracted by gene regulation.

Your research is unique, and we understand that standard products may not always fit. Our team of experts specializes in custom NHP sample collections. We can design a tailored protocol to meet your specific research requirements, including samples with unique anticoagulant types, customized volumes, or from specific disease models.