Category:
Non-Human Primate (NHP) related Antibody Products
GCLC Polyclonal Antibody (NHP-AB350)
Product Overview
Detailed Product Description
Technical Specifications
Product Property
Target Information
Downloadable Resources
Customer Reviews
This product is an antibody that was generated by immunizing rabbit against amino acids 295 - 313 of GCLC (Rat). It is used only in in vitro assays.
Introduction:
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.
Conjugate:
None
Applications:
IHC; IP
Host Species:
Rabbit
Species Reactivity:
Monkey; Mouse; Rat
Immunogen:
Amino acids 295 - 313 of GCLC (Rat)
Purification:
Protein A Column
Format:
Liquid
Concentration:
1 mg/mL
Buffer:
PBS, pH 7.4, 0.2% BSA, 0.09% sodium azide
Storage:
Short term: 4˚C. Long term: Store at -20˚C.
Clonality:
Polyclonal
Alternative Names:
gamma GCS-HS; Gamma-ECS; Gamma-glutamylcysteine synthetase; gamma-glutamylcysteine synthetase heavy subunit; GCS heavy chain; Glutamate--cysteine ligase catalytic subunit; glutamate-cysteine ligase, catalytic subunit; Glutamylcysteine gamma synthetase light chain
Entrez Gene ID:
2729
- GCLC Polyclonal Antibody (NHP-AB350) Data Sheet: Detailed information. datasheet
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