Category:
Non-Human Primate (NHP) related Antibody Products
GJA1 Polyclonal Antibody (NHP-AB352)
Product Overview
Detailed Product Description
Technical Specifications
Product Property
Target Information
Downloadable Resources
Customer Reviews
This product is an antibody that was generated by immunizing rabbit against a peptide located in the C-Terminal domain of GJA1 (Human). It is used only in in vitro assays.
Introduction:
GJA1 is a member of the gap junction protein family. Connexins assemble as a hexamer and are transported to the plasma membrane to create a hemichannel that can associate with hemichannels on nearby cells to create cell-to-cell channels. Clusters of these channels assemble to make gap junctions. Gap junction communication is important in development and regulation of cell growth. Phosphorylation of GJA1 is important in regulating assembly and function of gap junctions. Ser368 of GJA1 is phosphorylated by protein kinase C (PKC) after activation by phorbol esters, which decreases cell-to-cell communication. Src can interact with and phosphorylate GJA1 to alter gap junction communication. GFAP are membrane-spanning proteins that facilitate the transfer of ions and small molecules between cells.
Conjugate:
None
Applications:
IHC
Host Species:
Rabbit
Species Reactivity:
Bovine; Dog; Gibbon; Gorilla; Guinea Pig; Hamster; Human; Monkey; Mouse; Pig; Rabbit; Rat
Immunogen:
A peptide located in the C-Terminal domain of GJA1 (Human)
Purification:
Immunoaffinity Chromatography
Format:
Liquid
Concentration:
0.2 mg/mL
Buffer:
PBS, 0.1% sodium azide
Storage:
Short term: 4˚C. Long term: Store at -20˚C.
Clonality:
Polyclonal
Alternative Names:
alpha 1 connexin; connexin 43; Connexin-43; Cx-43; Cx43; CXA1; DFNB38; Gap junction 43 kDa heart protein; Gap junction alpha-1 protein; gap junction membrane channel protein alpha 1; gap junction protein, alpha 1, 43kDa; ODD; ODOD; SDTY3; Syndactyly type III
Entrez Gene ID:
2697
- GJA1 Polyclonal Antibody (NHP-AB352) Data Sheet: Detailed information. datasheet
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For research use only. Not intended for any clinical use.
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