PARL Polyclonal Antibody (NHP-AB496)

• This product is an antibody that was generated by immunizing rabbit against synthetic peptide to the C-terminus. It is used only in in vitro assays.

Detailed Product Description

• Introduction: Tropomyosin (Tpm-1)consists of a family of highly conserved, widely distributed actinbinding proteins involved in the contractile system of striated and smooth muscles and
  the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of
  actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it
  also functions in association with the troponin complex to regulate the calciumdependent interaction of actin and myosin during muscle contraction.
• Conjugate: None
• Antibody Isotype: IgG
• Applications: ELISA; IHC; WB

Technical Specifications

• Host Species: Rabbit
• Species Reactivity: Chicken; Human; Mouse; Monkey; Rat
• Immunogen: Synthetic peptide to the C-terminus

Product Property

• Purification: Affinity purification
• Format: Liquid

Target Information

• Clonality: Polyclonal
• Alternative Names: Presenilin associated, rhomboid-like protein , PSARL, PSARL1, RHBDS1, PRO2207, PSENIP2
• Entrez Gene ID: 55486
• Function: Required for normal embryonic brain and skeleton development, and for normal angiogenesis. Mediates the proteolytic cleavage of EphB2/CTF1 into EphB2/CTF2.