This product is comprised of an anti-FZD1 monoclonal antibody (Vantictumab) labeled with iFluor 750. iFluor 750 is a near-IR-fluorescent dye and it's excitation/emission is 749/775 nm.
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues.