CD11b Monoclonal Antibody (JES15A) (NHP-AB108)

• This product is an antibody that was generated by immunizing mouse against rheumatoid synovial cells and human monocytes. It is used only in in vitro assays.

Detailed Product Description

• Introduction: CD11b is the 165 kDa alphaM chain which combines with the CD18 beta2 integrin subunit to form the Mac-1 heterodimer. It is expressed on activated lymphocytes, monocytes, granulocytes and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and is a ligand for C3bi, CD50 (ICAM-3), CD54 (ICAM-1) and CD102 (ICAM-2).
• Conjugate: None
• Antibody Isotype: IgG1
• Applications: Flow Cytometry

Technical Specifications

• Host Species: Mouse
• Species Reactivity: Baboon; Chimpanzee; Human; Porcine
• Immunogen: Rheumatoid synovial cells and human monocytes

Product Property

• Format: Liquid
• Concentration: 0.1 mg/mL
• Buffer: Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
• Storage: Store at 4⁰C.

Target Information

• Target: CD11b
• Clone: JES15A
• Clonality: Monoclonal
• Alternative Names: Integrin alphaM, Mac-1alpha, Mac-1, Mo1, CR3, C3biR
• Entrez Gene ID: 3684