CD9 Monoclonal Antibody (SP38) (NHP-AB192)

• This product is an antibody that is used only in in vitro assays.

Detailed Product Description

• Introduction: CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and by neurons and glial cells in the peripheral nervous system. CD9 belongs to a family of membrane proteins termed tetraspanins which transverse the membrane four times. In pre B cells and platelets, CD9 antigen regulates cell activation and aggregation possibly through an association with the integrin CD41 / CD61 (GPIIb / GPIIIa). CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion, plays roles in cell attachment and proliferation and is necessary for association of heterologous MHC II molecules on the dendritic cell plasma membrane which is important for effective T cell stimulation.
• Conjugate: None
• Antibody Isotype: IgG2b
• Applications: Activity; Flow Cytometry; IHC-Fr; IP

Technical Specifications

• Host Species: Mouse
• Species Reactivity: Feline; Hamster; Human; Monkey; Rabbit

Product Property

• Format: Liquid
• Concentration: 0.1 mg/mL
• Buffer: Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
• Storage: Store at 4⁰C.

Target Information

• Target: CD9
• Clone: SP38
• Clonality: Monoclonal
• Alternative Names: 5H9; 5H9 antigen; antigen CD9; BA-2/p24 antigen; BA2; CD9; CD9 antigen; CD9 antigen (p24); Cell growth-inhibiting gene 2 protein; Leukocyte antigen MIC3; motility related protein-1; Motility-related protein; MRP-1; p24; sCD 9; sCD9; soluble CD 9; soluble CD9; Tetraspanin-29; Tetraspanin29; Tspan-29
• Entrez Gene ID: 928
• Function: CD9 functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression plays a critical role in the suppression of cancer cell motility and metastasis. CD9 is also considered as metastasis suppressor in solid tumors.