Cytochrome c Monoclonal Antibody (DC72.F6) (NHP-AB210)

• This product is an antibody that was generated by immunizing mouse against horse cytochrome c. It is used only in in vitro assays.

Detailed Product Description

• Introduction: Cytochrome C is an electron transporting protein that resides within the intermembrane space of the mitochondria, where it plays a critical role in oxidative phosphorylation and the production of cellular ATP. Release of cytochrome C from the mitochondria to the cytosol is triggered by apoptotic stimuli. In the cytoplasm, the cytochrome C binds apoptotic protease activating factor which activates the apoptotic initiator procaspase 9. Cytosolic cytochrome C functions in the activation of caspase 3, an ICE family molecule that is a key effector of apoptosis.
• Conjugate: None
• Antibody Isotype: IgG2a
• Applications: WB

Technical Specifications

• Host Species: Mouse
• Species Reactivity: Goat; Human; Monkey; Mouse; Rat; Sheep
• Immunogen: Horse cytochrome c

Product Property

• Purification: SDS-PAGE
• Format: Liquid
• Buffer: PBS containing 0.02% sodium azide
• Storage: Store at 4⁰C. Avoid freeze-thaw cycles.

Target Information

• Target: Cytochrome c
• Clone: DC72.F6
• Clonality: Monoclonal
• Alternative Names: Cytochrome c; Cytochrome C, expressed in somatic tissues; Cytochrome c, somatic; hc1
• Entrez Gene ID: 100053958