Category:
Non-Human Primate (NHP) related Antibody Products
Dopamine β-Hydroxylase Polyclonal Antibody (NHP-AB329)
Product Overview
Detailed Product Description
Technical Specifications
Product Property
Target Information
Downloadable Resources
Customer Reviews
This product is an antibody that was generated by immunizing rabbit against a peptide from the C-terminal region of human DBH. It is used only in in vitro assays.
Introduction:
Dopamine β-Hydroxylase (DBH) is an enzyme of the copper type II ascorbate-dependent mono-oxygenase family. This enzyme forms homotetramers composed of two noncovalently bound disulfide-linked dimers and is found as both membrane-associated and soluble forms. The soluble form is present in the lumen of secretory granules and is released from cells by exocytosis. DBH converts dopamine to noradrenaline. Deficiency in this enzyme causes a rare disease characterized by a complete absence of noradrenaline and adrenaline in plasma together with increased plasma dopamine levels. Orthostatic hypotension, the main symptom of DBH deficiency, can be alleviated by administration of dihydroxyphenylserine, a synthetic precursor of noradrenaline.
Conjugate:
None
Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Bovine; Monkey
Immunogen:
A peptide from the C-terminal region of human DBH
Purification:
Affinity Purified
Format:
Liquid
Storage:
Short term: 4˚C. Long term: Store at -20˚C.
Clonality:
Polyclonal
Entrez Gene ID:
1621
- Dopamine β-Hydroxylase Polyclonal Antibody (NHP-AB329) Data Sheet: Detailed information. datasheet
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For research use only. Not intended for any clinical use.
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