This product is an antibody that was generated by immunizing rabbit against an internal peptide of EIF3F (Human) 114-125. It is used only in in vitro assays.
IntroductionComponent of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
ConjugateNone
Applications ELISA; IF; IHC; IP; WB
Host SpeciesRabbit
Species Reactivity Bovine; Chicken; Chimpanzee; Human; Mouse; Rat
ImmunogenAn internal peptide of EIF3F (Human) 114-125
PurificationImmunoaffinity Chromatography
FormatLiquid
Concentration1 mg/mL
Buffer0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.
StorageStore at 4 or -20⁰C. Avoid freeze-thaw cycles.
EIF3F Polyclonal Antibody (NHP-AB264) Data Sheet: Detailed information. datasheet
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