- This product is an antibody that was generated by immunizing rabbit against an internal peptide of EIF3F (Human) 114-125. It is used only in in vitro assays.
Detailed Product Description
- Introduction: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
- Conjugate: None
- Applications: ELISA; IF; IHC; IP; WB
Technical Specifications
- Host Species: Rabbit
- Species Reactivity: Bovine; Chicken; Chimpanzee; Human; Mouse; Rat
- Immunogen: An internal peptide of EIF3F (Human) 114-125
Product Property
- Purification: Immunoaffinity Chromatography
- Format: Liquid
- Concentration: 1 mg/mL
- Buffer: 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.
- Storage: Store at 4 or -20⁰C. Avoid freeze-thaw cycles.
Target Information
- Clonality: Polyclonal
- Alternative Names: Deubiquitinating enzyme eIF3f; eIF-3-epsilon; eIF3 p47; eIF3-epsilon; EIF3F; Eukaryotic translation initiation factor 3 subunit 5; Eukaryotic translation initiation factor 3 subunit F; eukaryotic translation initiation factor 3, subunit 5 (epsilon, 47kD); eukaryotic translation initiation factor 3, subunit 5 epsilon, 47kDa; eukaryotic translation initiation factor 3, subunit F
- Entrez Gene ID: 8665
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