Category:
Non-Human Primate (NHP) related Antibody Products
IL-4 Monoclonal Antibody (R4LA) (NHP-AB135)
Product Overview
Detailed Product Description
Technical Specifications
Product Property
Target Information
Downloadable Resources
Customer Reviews
This product is an antibody that was generated by immunizing rat against CHO-expressed human IL-4. It is used only in in vitro assays.
Introduction:
Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.
Conjugate:
None
Antibody Isotype:
IgG1
Applications:
Flow Cytometry; ICC; IHC-Fr; IHC-P; IP
Host Species:
Rat
Species Reactivity:
Baboon; Human
Immunogen:
CHO-expressed human IL-4
Format:
Liquid
Concentration:
0.5 mg/mL
Buffer:
Supplied in PBS
Storage:
Store at 4⁰C.
Target:
IL-4
Clone:
R4LA
Clonality:
Monoclonal
Alternative Names:
B-cell growth factor 1; B-cell IgG differentiation factor; B-cell stimulatory factor 1; BSF-1; H-IL-4; IGG1 induction factor; IL-4; ILN; Interleukin; Interleukin-4; Interleukin4; Lymphocyte stimulatory factor 1; M-IL-4; MGC79402
Entrez Gene ID:
3565
- IL-4 Monoclonal Antibody (R4LA) (NHP-AB135) Data Sheet: Detailed information. datasheet
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For research use only. Not intended for any clinical use.
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