Category:
Non-Human Primate (NHP) related Antibody Products
IL-5 Monoclonal Antibody (A7L6) (NHP-AB137)
Product Overview
Detailed Product Description
Technical Specifications
Product Property
Target Information
Downloadable Resources
Customer Reviews
This product is an antibody that was generated by immunizing rat against COS-expressed human IL-5. It is used only in in vitro assays.
Introduction:
IL-5 is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. IL-5 cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes. The receptor of IL-5 cytokine is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). IL-5, together with those for interleukin 4 (IL4), interleukin 13 (IL13), and CSF2, form a cytokine gene cluster on chromosome 5. IL-5, IL4, and IL13 are found to be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.
Conjugate:
None
Antibody Isotype:
IgG2a
Applications:
Flow Cytometry; ICC; IHC-Fr; IHC-P
Host Species:
Rat
Species Reactivity:
Baboon; Human
Immunogen:
COS-expressed human IL-5
Format:
Liquid
Concentration:
0.5 mg/mL
Buffer:
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Storage:
Store at 4⁰C.
Target:
IL-5
Clone:
A7L6
Clonality:
Monoclonal
Alternative Names:
B-cell differentiation factor I; B-cell growth factor II; BCGF-II; colony-stimulating factor, eosinophil; Cytotoxic T-lymphocyte inducer; Eosinophil differentiation factor; IL-5; ILN; Interleukin; Interleukin-5; Interleukin5; T-cell replacing factor; TRF
Entrez Gene ID:
3567
- IL-5 Monoclonal Antibody (A7L6) (NHP-AB137) Data Sheet: Detailed information. datasheet
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For research use only. Not intended for any clinical use.
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