IL-5 Monoclonal Antibody (A7L6) (NHP-AB137)

• This product is an antibody that was generated by immunizing rat against COS-expressed human IL-5. It is used only in in vitro assays.

Detailed Product Description

• Introduction: IL-5 is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. IL-5 cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes. The receptor of IL-5 cytokine is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). IL-5, together with those for interleukin 4 (IL4), interleukin 13 (IL13), and CSF2, form a cytokine gene cluster on chromosome 5. IL-5, IL4, and IL13 are found to be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.
• Conjugate: None
• Antibody Isotype: IgG2a
• Applications: Flow Cytometry; ICC; IHC-Fr; IHC-P

Technical Specifications

• Host Species: Rat
• Species Reactivity: Baboon; Human
• Immunogen: COS-expressed human IL-5

Product Property

• Format: Liquid
• Concentration: 0.5 mg/mL
• Buffer: Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
• Storage: Store at 4⁰C.

Target Information

• Target: IL-5
• Clone: A7L6
• Clonality: Monoclonal
• Alternative Names: B-cell differentiation factor I; B-cell growth factor II; BCGF-II; colony-stimulating factor, eosinophil; Cytotoxic T-lymphocyte inducer; Eosinophil differentiation factor; IL-5; ILN; Interleukin; Interleukin-5; Interleukin5; T-cell replacing factor; TRF
• Entrez Gene ID: 3567