IL-24 Polyclonal Antibody (NHP-AB386)

• This product is an antibody that was generated by immunizing rabbit against a portion of amino acids 100 - 150 of IL - 24 (Human). It is used only in in vitro assays.

Detailed Product Description

• Introduction: Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.
• Conjugate: None
• Antibody Isotype: IgG
• Applications: Flow Cytometry; IHC; WB

Technical Specifications

• Host Species: Rabbit
• Species Reactivity: Gorilla; Human; Monkey
• Immunogen: A portion of amino acids 100 - 150 of IL - 24 (Human)

Product Property

• Purification: Protein G Column
• Format: Liquid
• Concentration: 0.5 mg/mL
• Buffer: PBS, 0.2% gelatin, 0.05% sodium azide
• Storage: Short term: 4˚C. Long term: Store at -20˚C.

Target Information

• Clonality: Polyclonal
• Alternative Names: IL 24; IL-24; IL-4-induced secreted protein; Interleukin-24; MDA-7; melanocyte-associated Mda-7; Melanoma differentiation-associated gene 7 protein; suppression of tumorigenicity 16 (melanoma differentiation); Suppression of tumorigenicity 16 protein
• Entrez Gene ID: 11009