Category:
Non-Human Primate (NHP) related Antibody Products
IL-24 Polyclonal Antibody (NHP-AB386)
Product Overview
Detailed Product Description
Technical Specifications
Product Property
Target Information
Downloadable Resources
Customer Reviews
This product is an antibody that was generated by immunizing rabbit against a portion of amino acids 100 - 150 of IL - 24 (Human). It is used only in in vitro assays.
Introduction:
Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.
Conjugate:
None
Antibody Isotype:
IgG
Applications:
Flow Cytometry; IHC; WB
Host Species:
Rabbit
Species Reactivity:
Gorilla; Human; Monkey
Immunogen:
A portion of amino acids 100 - 150 of IL - 24 (Human)
Purification:
Protein G Column
Format:
Liquid
Concentration:
0.5 mg/mL
Buffer:
PBS, 0.2% gelatin, 0.05% sodium azide
Storage:
Short term: 4˚C. Long term: Store at -20˚C.
Clonality:
Polyclonal
Alternative Names:
IL 24; IL-24; IL-4-induced secreted protein; Interleukin-24; MDA-7; melanocyte-associated Mda-7; Melanoma differentiation-associated gene 7 protein; suppression of tumorigenicity 16 (melanoma differentiation); Suppression of tumorigenicity 16 protein
Entrez Gene ID:
11009
- IL-24 Polyclonal Antibody (NHP-AB386) Data Sheet: Detailed information. datasheet
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For research use only. Not intended for any clinical use.
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