Category:
Non-Human Primate (NHP) related Antibody Products
PDGFRB Polyclonal Antibody (NHP-AB420)
Product Overview
Detailed Product Description
Technical Specifications
Product Property
Target Information
Downloadable Resources
Customer Reviews
This product is an antibody that was generated by immunizing rabbit against a peptide located near the Extracellular domain of PDGFRB (Human). It is used only in in vitro assays.
Introduction:
PDGFRb is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. The gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.
Conjugate:
None
Applications:
IHC-P
Host Species:
Rabbit
Species Reactivity:
Bovine; Gibbon; Gorilla; Human; Monkey; Pig; Rabbit
Immunogen:
A peptide located near the Extracellular domain of PDGFRB (Human)
Purification:
Immunoaffinity Chromatography
Format:
Liquid
Concentration:
1 mg/mL
Buffer:
PBS, 0.1% sodium azide
Storage:
Short term: 4˚C. Long term: Store at -20˚C.
Clonality:
Polyclonal
Alternative Names:
Beta platelet-derived growth factor receptor; Beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; CD140b; CD140b antigen; PDGF beta chain; PDGF Receptor beta; PDGF-R-beta; PDGFR-1; PDGFR-beta; Platelet-derived growth factor receptor 1; Platelet-derived growth factor receptor beta; platelet-derived growth factor receptor beta variant 1
Entrez Gene ID:
5159
- PDGFRB Polyclonal Antibody (NHP-AB420) Data Sheet: Detailed information. datasheet
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