SLITRK6 Polyclonal Antibody (NHP-AB463)

• This product is an antibody that was generated by immunizing rabbit against synthetic 14 amino acid peptide from internal region of human SLITRK6. It is used only in in vitro assays.

Detailed Product Description

• Introduction: SLITRK6 is a member a protein family consisting of six homologous transmembrane proteins (SLITRK1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. SLITRK6 expression has been observed in tissues such as tongue, lung, gastrointestinal tract, and pancreas. Like every other Slitrk protein except SLITRK1, overexpression of SLITRK6 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth. At least two isoforms of SLITRK6 are known to exist.
• Conjugate: None
• Applications: IHC

Technical Specifications

• Host Species: Rabbit
• Species Reactivity: Bat; Bovine; Dog; Gibbon; Human; Monkey; Pig
• Immunogen: Synthetic 14 amino acid peptide from internal region of human SLITRK6

Product Property

• Purification: Immunoaffinity Chromatography
• Format: Liquid
• Concentration: 1 mg/mL
• Buffer: PBS, 0.1% sodium azide
• Storage: Short term: 4˚C. Long term: Store at -20˚C.

Target Information

• Clonality: Polyclonal
• Alternative Names: 4832410J21Rik; neuronal transmembrane protein Slitrk6; RP11-272M24.2; SLIT and NTRK-like family, member 6; SLIT and NTRK-like protein 6; slit and trk like gene 6
• Entrez Gene ID: 84189