ZMYM2 Polyclonal Antibody (NHP-AB491)

• This product is an antibody that was generated by immunizing rabbit against a portion of amino acids 1250-1300 of human Zinc finger protein 198. It is used only in in vitro assays.

Detailed Product Description

• Introduction: Zinc finger MYM-type protein 2 is a nuclear protein that may function as a transcription factor. Two isoforms of Zinc finger MYM-type protein 2 have been described that are produced by alternative splicing. The SUMO-interacting motifs (SIM) of Zinc finger MYM-type protein 2 are shown to be essential for its recruitment to chromatin. The SIM motifs play an important role in its gene-regulatory activities, however, they are not required for the intrinsic transcriptional repressive properties of Zinc finger MYM-type protein 2. A chromosomal aberration involving ZMYM2 is reported to cause stem cell leukemia lymphoma syndrome (SCLL), which is characterized as lymphoblastic lymphoma in association with a myeloproliferative disorder accompanied by pronounced peripheral eosinophilia and/or prominent eosinophilic infiltrates in the affected bone marrow.
• Conjugate: None
• Antibody Isotype: IgG
• Applications: IHC; WB

Technical Specifications

• Host Species: Rabbit
• Species Reactivity: Bovine; Chicken; Dog; Human; Monkey; Mouse; Orangutan; Rat
• Immunogen: A portion of amino acids 1250-1300 of human Zinc finger protein 198

Product Property

• Purification: Immunoaffinity Chromatography
• Format: Liquid
• Concentration: 0.5 mg/mL
• Buffer: PBS, 0.2% gelatin, 0.05% sodium azide
• Storage: Short term: 4˚C. Long term: Store at -20˚C.

Target Information

• Clonality: Polyclonal
• Alternative Names: Fused in myeloproliferative disorders protein; rearranged in an atypical myeloproliferative disorder; Rearranged in atypical myeloproliferative disorder protein; RP11-264J4.7; Zinc finger MYM-type protein 2; Zinc finger protein 198; zinc finger, MYM-type 2
• Entrez Gene ID: 7750