Category:
Non-Human Primate (NHP) related Antibody Products
ZMYM2 Polyclonal Antibody (NHP-AB491)
Product Overview
Detailed Product Description
Technical Specifications
Product Property
Target Information
Downloadable Resources
Customer Reviews
This product is an antibody that was generated by immunizing rabbit against a portion of amino acids 1250-1300 of human Zinc finger protein 198. It is used only in in vitro assays.
Introduction
Zinc finger MYM-type protein 2 is a nuclear protein that may function as a transcription factor. Two isoforms of Zinc finger MYM-type protein 2 have been described that are produced by alternative splicing. The SUMO-interacting motifs (SIM) of Zinc finger MYM-type protein 2 are shown to be essential for its recruitment to chromatin. The SIM motifs play an important role in its gene-regulatory activities, however, they are not required for the intrinsic transcriptional repressive properties of Zinc finger MYM-type protein 2. A chromosomal aberration involving ZMYM2 is reported to cause stem cell leukemia lymphoma syndrome (SCLL), which is characterized as lymphoblastic lymphoma in association with a myeloproliferative disorder accompanied by pronounced peripheral eosinophilia and/or prominent eosinophilic infiltrates in the affected bone marrow.
Conjugate
None
Antibody Isotype
IgG
Applications
IHC; WB
Host Species
Rabbit
Species Reactivity
Bovine; Chicken; Dog; Human; Monkey; Mouse; Orangutan; Rat
Immunogen
A portion of amino acids 1250-1300 of human Zinc finger protein 198
Purification
Immunoaffinity Chromatography
Format
Liquid
Concentration
0.5 mg/mL
Buffer
PBS, 0.2% gelatin, 0.05% sodium azide
Storage
Short term: 4˚C. Long term: Store at -20˚C.
Clonality
Polyclonal
Alternative Names
Fused in myeloproliferative disorders protein; rearranged in an atypical myeloproliferative disorder; Rearranged in atypical myeloproliferative disorder protein; RP11-264J4.7; Zinc finger MYM-type protein 2; Zinc finger protein 198; zinc finger, MYM-type 2
Entrez Gene ID
7750
- ZMYM2 Polyclonal Antibody (NHP-AB491) Data Sheet: Detailed information. datasheet
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For research use only. Not intended for any clinical use.
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