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DL-Dithiothreitol/DTT - pure grade (CAT#: ADC-P-083)

ADCs Toxins, Used in molecular biology. DTT preserves proteins of interiors of cells in their functional form by avoiding the oxidation of Sulfhidril-groups (SH-) into disulifidbridges through atmospheric oxygen. On the other hand the convolution of proteins whose structure is stabilised by disulfidbridges may be destroyed by their reduction. It is an important reagent in the course of SDS-PAGE and Western-Blotting respectively.

  • Product Information
  • CAS NO
  • 3483-12-3
  • Description
  • ADCs Toxins, Used in molecular biology. DTT preserves proteins of interiors of cells in their functional form by avoiding the oxidation of Sulfhidril-groups (SH-) into disulifidbridges through atmospheric oxygen. On the other hand the convolution of proteins whose structure is stabilised by disulfidbridges may be destroyed by their reduction. It is an important reagent in the course of SDS-PAGE and Western-Blotting respectively.
  • Classification
  • Others
  • Molecular Weight
  • 154,25
  • Purity
  • 95%

For Research Use Only. NOT FOR CLINICAL USE.

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Customer Reviews FAQ
def-person
Excellent
Dithiothreitol (DTT) played a crucial role in our protein preparation experiments. It effectively prevented oxidation of sulfhydryl groups, preserving protein functionality during SDS-PAGE and Western blotting.
def-person
Excellent
In our ADC research, DTT was essential for reducing disulfide bonds during drug conjugation. It allowed us to maintain protein stability while optimizing the conjugation process for better results.
def-person
Excellent
DTT was indispensable in our protein assays, particularly in maintaining the native structure of intracellular proteins. Its ability to prevent oxidation made a significant difference in our experimental outcomes.
def-person
Excellent
We utilized DTT in ADC development, and it effectively reduced disulfide bonds, allowing for precise conjugation between antibodies and cytotoxins. This was key in improving the efficacy of our conjugates.
def-person
Excellent
Using DTT in our molecular biology experiments helped maintain the integrity of proteins during preparation. It ensured that oxidation did not compromise our results, leading to more reliable data.

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