CD5 Monoclonal Antibody (X3A9) (NHP-AB254)

• This product is an antibody that was generated by immunizing mouse against stimulated human leukocytes. It is used only in in vitro assays.

Detailed Product Description

• Introduction: CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein. CD5 is present on all mature T-lymphocytes, on most of thymocytes and on many T-cell leukemias and lymphomas. CD5 also reacts with a subpopulation of activated B-cells and may act as a receptor in regulating T-cell proliferation. CD5 is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. CD5 is expressed by many T cell leukemia, lymphomas, and activated T cells. Diseases associated with CD5 dysfunction include thymus cancer and Richter's Syndrome.
• Conjugate: None
• Antibody Isotype: IgG2aκ
• Applications: Flow Cytometry; Func; IF

Technical Specifications

• Host Species: Mouse
• Species Reactivity: Human; Rhesus
• Immunogen: Stimulated human leukocytes

Product Property

• Purification: Protein G affinity chromatography
• Format: Liquid
• Concentration: 0.2 mg/mL
• Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
• Storage: Store at 4⁰C. Avoid freez-thaw cycles.

Target Information

• Clone: X3A9
• Clonality: Monoclonal
• Alternative Names: CD antigen CD5; CD5; CD5 antigen p56-62; fCD5; Ly-1; Lymphocyte antigen 1; Pan T cell; T-cell surface glycoprotein CD5
• Entrez Gene ID: 921