DRD3 Polyclonal Antibody (NHP-AB261)

• This product is an antibody that was generated by immunizing rabbit against a peptide located in the 3rd cytoplasmic domain of DRD3 (Human). It is used only in in vitro assays.

Detailed Product Description

• Introduction: This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).
• Conjugate: None
• Applications: ELISA; IHC

Technical Specifications

• Host Species: Rabbit
• Species Reactivity: Chimpanzee; Gorilla; Human; Monkey
• Immunogen: A peptide located in the 3rd cytoplasmic domain of DRD3 (Human)

Product Property

• Purification: Immunoaffinity Chromatography
• Format: Liquid
• Concentration: 1 mg/mL
• Buffer: PBS, 0.1% sodium azide.
• Storage: Short term: 4˚C. Long term: Store at -80˚C. Avoid freeze-thaw cycles.

Target Information

• Clonality: Polyclonal
• Alternative Names: D(3) dopamine receptor; D3 receptor; D3nf; Dopamine 3 receptor; Dopamine D3 receptor; dopamine receptor 3; dopaminergic receptor D3; essential tremor 1
• Entrez Gene ID: 1814